Search on: DNA LIGASES 
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Descriptor English:   DNA Ligases 
Descriptor Spanish:   ADN Ligasas 
Descriptor Portuguese:   DNA Ligases 
Synonyms English:   T4 DNA Ligase
DNA Ligase, T4
Joinases, DNA
Ligase, T4 DNA
Ligases, DNA
Ligases, Polydeoxyribonucleotide
Synthetases, Polydeoxyribonucleotide
DNA Joinases
Polydeoxyribonucleotide Ligases
Polydeoxyribonucleotide Synthetases  
Tree Number:   D08.811.074.500
D08.811.464.754.600
Definition English:   Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD). 
Indexing Annotation English:   do not confuse X ref POLYDEOXYRIBONUCLEOTIDE SYNTHETASES with X ref POLYRIBONUCLEOTIDE SYNTHETASE
History Note English:   98(77); for DNA LIGASES use POLYNUCLEOTIDE SYNTHETASES 1973-76 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   11522 
Unique Identifier:   D011088 

Occurrence in VHL:
 

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